STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHA64315.1UPF0284 protein; TIGRFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative; HAMAP: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative; KEGG: pmf:P9303_06331 hypothetical protein; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like; Belongs to the UPF0284 family. (405 aa)    
Predicted Functional Partners:
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
  
 
 0.932
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.852
EHA64314.1
PFAM: Protein of unknown function DUF2232, membrane; KEGG: pmf:P9303_06321 hypothetical protein.
 
     0.836
EHA61867.1
PFAM: Aminotransferase, class I/classII; KEGG: pmf:P9303_27901 aminotransferases class-I.
 
 
 0.836
EHA59281.1
precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: pmt:PMT1772 bifunctional CbiH protein and precorrin-3B C17-methyltransferase; PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; Tetrapyrrole methylase.
  
  
 0.822
EHA63350.1
Cobalbumin biosynthesis protein; PFAM: Cobinamide kinase/cobinamide phosphate guanyltransferase; KEGG: pmt:PMT0749 putative cobinamide kinase.
  
 
 0.819
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
 
 0.816
EHA64313.1
KEGG: pmf:P9303_06311 hypothetical protein.
       0.800
EHA64316.1
KEGG: pmt:PMT1349 hypothetical protein.
       0.790
EHA61838.1
Histidinol-phosphate transaminase; KEGG: pmt:PMT2069 aminotransferase class-I; PFAM: Aminotransferase, class I/classII.
  
 
 0.746
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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