STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
EHA62202.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (436 aa)    
Predicted Functional Partners:
panC/cmk
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family.
 
  
 0.944
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.926
EHA60593.1
Putative transcriptional acitvator, Baf family; KEGG: pmt:PMT1623 hypothetical protein; TIGRFAM: Type III pantothenate kinase; PFAM: Type III pantothenate kinase.
  
 
 0.897
EHA63841.1
Aspartate transaminase; KEGG: pmt:PMT0779 aminotransferase class-I; PFAM: Aminotransferase, class I/classII.
  
  0.894
EHA62203.1
PFAM: Protein of unknown function DUF2555; KEGG: pmf:P9303_23881 hypothetical protein.
     
 0.833
EHA64307.1
KEGG: pmt:PMT1359 putative biotin--acetyl-CoA-carboxylase ligase; TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase.
    
 0.724
coaE
Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
   
 0.653
priA
Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
  
    0.645
EHA60657.1
TIGRFAM: Cysteine synthase K/M; Cysteine synthase A; KEGG: pmt:PMT1978 O-acetylserine (thiol)-lyase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.617
EHA60201.1
TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; KEGG: pmj:P9211_04051 O-acetylserine (thiol)-lyase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.617
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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