Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHA62277.1PFAM: Domain of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated domain; KEGG: pmf:P9303_24941 hemolysin-like protein. (425 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
 0.928
EHA62276.1
Oxidoreductase domain protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; KEGG: pmf:P9303_24931 putative oxidoreductase.
 
    0.740
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
     0.559
EHA62280.1
Folate-binding protein YgfZ; KEGG: pmf:P9303_24971 aminomethyltransferase GcvT-like protein; TIGRFAM: Folate-binding, YgfZ; PFAM: Glycine cleavage T-protein, N-terminal.
 
     0.556
purH
Bifunctional purine biosynthesis protein purH; KEGG: pmf:P9303_24851 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme, transformylase domain; Methylglyoxal synthase-like domain; TIGRFAM: AICARFT/IMPCHase bienzyme; HAMAP: AICARFT/IMPCHase bienzyme; SMART: AICARFT/IMPCHase bienzyme, transformylase domain; Methylglyoxal synthase-like domain.
    
  0.539
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.536
EHA62278.1
KEGG: pmt:PMT1867 occludin/ELL family.
       0.526
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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