Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHA62342.1PFAM: Alpha/beta hydrolase fold-1; KEGG: pmn:PMN2A_1174 alpha/beta fold family hydrolase. (318 aa)    
Predicted Functional Partners:
EHA62472.1
KR domain protein; KEGG: gvi:gll4226 modular polyketide synthase; PFAM: Polyketide synthase, KR; SMART: Polyketide synthase/Fatty acid synthase, KR.
 
 0.938
EHA62471.1
PFAM: Beta-ketoacyl synthase, N-terminal; 2-nitropropane dioxygenase, NPD; Beta-ketoacyl synthase, C-terminal; Acyl transferase; Phosphopantetheine-binding; KEGG: gvi:gll4226 modular polyketide synthase; SMART: Polyketide synthase, beta-ketoacyl synthase domain; Polyketide synthase, acyl transferase domain.
 
 0.936
EHA62341.1
PFAM: Aldose 1-epimerase; KEGG: pmt:PMT1942 hypothetical protein.
       0.732
EHA60204.1
Dihydrolipoyllysine-residue acetyltransferase; KEGG: pmt:PMT0220 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding.
    
  0.671
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
   
  0.630
rpsB
KEGG: pmt:PMT0584 30S ribosomal protein S2; TIGRFAM: Ribosomal protein S2, bacteria/mitochondria/plastid; PFAM: Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
   
  0.628
rpsJ
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
    
  0.627
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.626
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
    
  0.623
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
     
 0.615
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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