Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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EHA62438.1Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; KEGG: pmf:P9303_01941 Tfp pilus assembly protein PilF. (269 aa)    
Predicted Functional Partners:
EHA60532.1
PFAM: Tetratricopeptide TPR-1; KEGG: amr:AM1_5932 pentapeptide repeat-containing serine/threonine kinase.
 
 
  0.839
EHA62437.1
Amidohydrolase; TIGRFAM: Peptidase M20D, amidohydrolase; KEGG: pmt:PMT0158 zinc metallopeptidase; PFAM: Peptidase M20; Peptidase M20, dimerisation.
       0.815
ruvB
Holliday junction ATP-dependent DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
       0.815
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.806
EHA63474.1
PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; KEGG: pmf:P9303_28691 hypothetical protein.
 
 
0.789
EHA62435.1
KEGG: cyc:PCC7424_1391 heat domain containing protein.
       0.773
EHA62436.1
KEGG: pmt:PMT0159 hypothetical protein.
       0.773
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
  0.766
EHA59106.1
PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; KEGG: pmt:PMT0006 hypothetical protein.
  
     0.762
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.633
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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