Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
menA1,4-dihydroxy-2-naphthoate phytyltransferase; Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4- naphthoquinone; Belongs to the MenA family. Type 2 subfamily. (314 aa)    
Predicted Functional Partners:
EHA63622.1
TIGRFAM: Solanesyl diphosphate synthase; KEGG: pmj:P9211_10311 polyprenyl synthetase; solanesyl diphosphate synthase (sds); PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
  
 0.886
EHA61828.1
TIGRFAM: Isochorismate synthase; KEGG: pmf:P9303_27351 isochorismate synthase; PFAM: Chorismate binding, C-terminal.
 
   
 0.860
EHA63297.1
TIGRFAM: Geranylgeranyl reductase, plant/cyanobacteria; Geranylgeranyl reductase; Geranylgeranyl reductase, plant/prokaryotic; KEGG: pmj:P9211_10031 aromatic-ring hydroxylase (flavoprotein monooxygenase).
  
 
  0.856
EHA60595.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pmf:P9303_02581 putative NADH dehydrogenase, transport associated.
    
  0.855
EHA61826.1
KEGG: pmt:PMT2058 putative O-succinylbenzoate synthase; PFAM: Mandelate racemase/muconate lactonizing enzyme, C-terminal; SMART: Mandelate racemase/muconate lactonizing enzyme, C-terminal.
 
   
 0.848
menG
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of 2-phytyl- 1,4-beta-naphthoquinol to phylloquinol.
  
  
 0.831
EHA61822.1
1,4-dihydroxy-2-naphthoyl-CoA hydrolase; Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis; Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily.
  
  
 0.811
EHA61825.1
o-succinylbenzoate--CoA ligase; KEGG: pmf:P9303_27321 putative O-succinylbenzoic acid--CoA ligase (OSB-CoA synthetase); PFAM: AMP-dependent synthetase/ligase.
 
   
 0.745
EHA59093.1
TIGRFAM: Sucrose-phosphate synthase, glycosyltransferase domain; Sucrose phosphate synthase, sucrose phosphatase-like domain; KEGG: pmf:P9303_30171 sucrose phosphate synthase; PFAM: Sucrose-phosphate synthase; Glycosyl transferase, group 1; Sucrose synthase.
  
  
  0.731
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
   
 0.692
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.