Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EHA60383.1TIGRFAM: HAD-superfamily hydrolase, subfamily IA, hypothetical 1; KEGG: pmf:P9303_04971 putative imidazoleglycerol-phosphate dehydratase. (251 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
  0.863
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
 
 0.803
hisH
Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
    
  0.795
EHA61838.1
Histidinol-phosphate transaminase; KEGG: pmt:PMT2069 aminotransferase class-I; PFAM: Aminotransferase, class I/classII.
  
 
 0.793
EHA60382.1
30S ribosomal protein 3; Probably a ribosomal protein or a ribosome-associated protein; Belongs to the chloroplast-specific ribosomal protein cS23 family.
 
     0.786
EHA60384.1
PFAM: Sodium/calcium exchanger membrane region; KEGG: vsp:VS_II0239 calcium/proton antiporter.
       0.773
EHA63281.1
KEGG: pmt:PMT0793 ribonucleotide reductase (class II); TIGRFAM: Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent.
  
     0.727
EHA60360.1
KEGG: pmf:P9303_05231 hypothetical protein.
  
     0.727
EHA60637.1
KEGG: pmj:P9211_01241 hypothetical protein.
  
     0.725
EHA58612.1
KEGG: pmf:P9303_19361 hypothetical protein.
  
     0.685
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.