Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EHA60385.1PFAM: Peptidase M24, structural domain; Peptidase M24B, X-Pro dipeptidase/aminopeptidase P N-terminal; KEGG: pmf:P9303_04951 putative aminopeptidase P; Belongs to the peptidase M24B family. (446 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
  0.753
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
  
 0.733
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
    
  0.693
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
    
  0.693
EHA60204.1
Dihydrolipoyllysine-residue acetyltransferase; KEGG: pmt:PMT0220 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding.
 
  
 
 0.670
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
    
  0.669
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
     
  0.652
EHA60386.1
PFAM: Domain of unknown function DUF21; Cystathionine beta-synthase, core; KEGG: pmt:PMT1458 hypothetical protein.
  
    0.644
EHA60387.1
PFAM: GTP-binding protein, HSR1-related; KEGG: pmf:P9303_04921 GTPase SAR1.
       0.641
EHA60388.1
PFAM: Cytidylyltransferase; KEGG: pmt:PMT1460 nicotinic acid mononucleotide adenylyltransferase; Belongs to the NadD family.
       0.641
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
Server load: medium (48%) [HD]