Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHA60394.1KEGG: ach:Achl_3744 hypothetical protein. (124 aa)    
Predicted Functional Partners:
secA
Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
    
  0.734
EHA60393.1
Hypothetical protein.
       0.639
EHA60395.1
KEGG: pmt:PMT1463 hypothetical protein.
       0.590
EHA60396.1
KEGG: pma:Pro1602 hypothetical protein.
       0.503
EHA60397.1
KEGG: pmb:A9601_16511 ferredoxin; TIGRFAM: Ferredoxin [2Fe-2S], plant; PFAM: Ferredoxin.
       0.503
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
     
 0.482
EHA60398.1
TIGRFAM: Conserved hypothetical protein CHP02466; KEGG: syf:Synpcc7942_1296 hypothetical protein.
       0.474
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
     
 0.445
EHA61996.1
PFAM: Peptide chain release factor class I/class II; KEGG: pmf:P9303_29401 peptidyl-tRNA hydrolase domain protein.
 
     0.429
EHA64294.1
Membrane protein insertase, YidC/Oxa1 family; KEGG: pmt:PMT1371 putative inner membrane protein translocase component YidC; TIGRFAM: Membrane insertion protein, OxaA/YidC; PFAM: Membrane insertion protein, OxaA/YidC.
     
 0.422
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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