STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccsBCytochrome c biogenesis protein ccs1; Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment. (435 aa)    
Predicted Functional Partners:
ccsA
Cytochrome c biogenesis protein ccsA; Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
 
  
 0.970
EHA60413.1
PFAM: Cytochrome c assembly protein, transmembrane domain; KEGG: pmt:PMT1476 putative C-type cytochrome biogenesis protein CcdA.
 
  
 0.915
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
      
 0.619
EHA60412.1
PFAM: Cell cycle protein; KEGG: pmf:P9303_04731 cell division protein FtsW; Belongs to the SEDS family.
       0.583
EHA62039.1
TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; KEGG: pmf:P9303_29821 putative uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole methylase; Belongs to the precorrin methyltransferase family.
  
    0.464
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.430
EHA63463.1
PFAM: Protein of unknown function DUF185; KEGG: pmf:P9303_15581 hypothetical protein.
  
     0.426
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.416
EHA63025.1
TIGRFAM: Thioredoxin reductase; KEGG: pma:Pro1245 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Thioredoxin domain.
  
  
 0.413
petB
Cytochrome b/b6 domain protein; Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
  
   
 0.402
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.