STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHA60588.1AAA ATPase central domain protein; KEGG: pmf:P9303_02651 recombination factor protein RarA/unknown domain fusion protein; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core. (734 aa)    
Predicted Functional Partners:
EHA60243.1
TIGRFAM: DNA helicase, ATP-dependent, RecQ type; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; KEGG: pmf:P9303_21731 superfamily II DNA helicase; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal.
  
 
 
 0.841
EHA59101.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 
 0.752
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.573
EHA60585.1
KEGG: pmt:PMT1615 hypothetical protein.
       0.543
EHA60586.1
KEGG: pmf:P9303_02671 RND family multidrug efflux transporter; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: Acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.543
EHA60587.1
Efflux transporter, RND family, MFP subunit; KEGG: pmf:P9303_02661 membrane-fusion protein; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.543
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
    0.539
EHA62255.1
TIGRFAM: Competence-induced protein CinA; CinA, C-terminal; PFAM: CinA, C-terminal; Molybdopterin binding; KEGG: pmf:P9303_24701 molybdenum cofactor biosynthesis protein; SMART: Molybdopterin binding.
     
 0.461
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.441
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.