Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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Score
mnmAtRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (391 aa)    
Predicted Functional Partners:
EHA59339.1
UBA/THIF-type NAD/FAD binding protein; KEGG: pmf:P9303_22891 molybdopterin biosynthesis protein; PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; Rhodanese-like; SMART: Rhodanese-like.
    
 0.956
mnmE
tRNA modification GTPase mnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
 
 0.938
mnmG
tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
  
 0.934
EHA61816.1
Cysteine desulfurase; KEGG: pmf:P9303_27201 NifS-like aminotransferase class-V; PFAM: Aminotransferase, class V/Cysteine desulfurase.
 
 
 0.805
EHA63403.1
Cysteine desulfurase; KEGG: pmt:PMT0717 class-V aminotransferase family cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase.
 
 
 0.803
EHA63607.1
PFAM: Domain of unknown function DUF752; KEGG: pmf:P9303_18881 hypothetical protein.
     
 0.740
EHA58608.1
KEGG: pmf:P9303_19401 hypothetical protein; TIGRFAM: ThiS, thiamine-biosynthesis; PFAM: ThiamineS.
   
 
  0.738
EHA61801.1
KEGG: pmf:P9303_16081 rhodanese-like protein; PFAM: Rhodanese-like; SMART: Rhodanese-like.
     
 0.715
EHA63057.1
PFAM: Fe-S metabolism associated SufE; KEGG: pmf:P9303_08891 hypothetical protein.
     
 0.705
nnrD
YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family.
       0.704
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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