STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHA60204.1Dihydrolipoyllysine-residue acetyltransferase; KEGG: pmt:PMT0220 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding. (438 aa)    
Predicted Functional Partners:
EHA63667.1
Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.999
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.999
EHA60096.1
TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: pmf:P9303_19781 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
 0.999
EHA64140.1
KEGG: pmt:PMT0470 glutathione reductase (NADPH); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
 0.998
EHA61798.1
TIGRFAM: 2-methylcitrate synthase/citrate synthase type I; KEGG: pmf:P9303_26921 citrate synthase; PFAM: Citrate synthase-like; Belongs to the citrate synthase family.
  
 0.983
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.979
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
 0.964
EHA63639.1
FHA modulated glycosyl transferase/transpeptidase; KEGG: syf:Synpcc7942_2000 penicillin-binding protein 1A; PFAM: Glycosyl transferase, family 51; Forkhead-associated (FHA) domain; Penicillin-binding protein, transpeptidase; SMART: Forkhead-associated (FHA) domain.
    
 
 0.960
EHA64179.1
PFAM: Biotin/lipoate A/B protein ligase; KEGG: pmt:PMT1224 protein ligase.
  
 0.955
EHA59278.1
KEGG: pmt:PMT1777 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal.
     
 0.953
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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