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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHA59115.1Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (334 aa)    
Predicted Functional Partners:
EHA59116.1
TIGRFAM: Methionine sulphoxide reductase B; KEGG: pmf:P9303_00151 hypothetical protein; PFAM: Methionine sulphoxide reductase B.
       0.564
EHA63496.1
KEGG: tmz:Tmz1t_0608 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; TIGRFAM: Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, C-terminal.
    
   0.513
EHA59117.1
HI0933 family protein; KEGG: pmt:PMT0017 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00275, flavoprotein HI0933-like; PFAM: Conserved hypothetical protein CHP00275, flavoprotein HI0933-like.
       0.490
EHA63017.1
PFAM: N2,N2-dimethylguanosine tRNA methyltransferase; KEGG: pmf:P9303_08491 N2,N2-dimethylguanosine tRNA methyltransferase.
   
 
 0.486
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
 
 
 0.464
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
   
  
 0.444
EHA60594.1
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
    
   0.411
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
   
 
 0.409
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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