STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHA59119.1Twitching motility protein; TIGRFAM: Pilus retraction protein PilT; PFAM: Type II secretion system protein E; KEGG: pmf:P9303_00181 PilT1-like protein; SMART: ATPase, AAA+ type, core. (357 aa)    
Predicted Functional Partners:
EHA59118.1
PFAM: Type II secretion system F domain; KEGG: pmf:P9303_00171 pili biogenesis protein.
 
   
 0.980
EHA59120.1
PFAM: Type II secretion system protein E; KEGG: pmf:P9303_00191 general secretion pathway protein E.
 
 
0.942
EHA63879.1
Prepilin peptidase; KEGG: pmt:PMT0533 putative type 4 prepilin peptidase; PFAM: Peptidase A24A, N-terminal; Peptidase A24A, prepilin type IV.
 
   
 0.805
EHA60174.1
Pilin; KEGG: pmf:P9303_20881 pilin.
 
   
 0.594
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
       0.584
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
       0.470
EHA59123.1
KEGG: pmf:P9303_00221 hypothetical protein; Belongs to the sulfur carrier protein TusA family.
       0.469
EHA61918.1
CheW protein; KEGG: dak:DaAHT2_2535 response regulator receiver modulated CheW protein; PFAM: CheW-like protein; SMART: CheW-like protein.
     
 0.455
rsgA
Ribosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
       0.437
EHA60149.1
KEGG: pmf:P9303_20431 hypothetical protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein.
     
 0.424
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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