Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EHA59120.1PFAM: Type II secretion system protein E; KEGG: pmf:P9303_00191 general secretion pathway protein E. (583 aa)    
Predicted Functional Partners:
EHA59118.1
PFAM: Type II secretion system F domain; KEGG: pmf:P9303_00171 pili biogenesis protein.
 
 
 0.998
EHA60174.1
Pilin; KEGG: pmf:P9303_20881 pilin.
 
 0.943
EHA59119.1
Twitching motility protein; TIGRFAM: Pilus retraction protein PilT; PFAM: Type II secretion system protein E; KEGG: pmf:P9303_00181 PilT1-like protein; SMART: ATPase, AAA+ type, core.
 
 
0.939
EHA60176.1
Hypothetical protein; KEGG: syf:Synpcc7942_2590 pilin-like protein-like.
  
 0.913
EHA63879.1
Prepilin peptidase; KEGG: pmt:PMT0533 putative type 4 prepilin peptidase; PFAM: Peptidase A24A, N-terminal; Peptidase A24A, prepilin type IV.
 
 
 0.857
EHA64354.1
Twitching motility protein; TIGRFAM: Pilus retraction protein PilT; PFAM: Type II secretion system protein E; KEGG: pmt:PMT1313 homologous to PilT2 protein; SMART: ATPase, AAA+ type, core.
 
 
0.772
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
       0.646
EHA64392.1
KEGG: syn:sll1386 hypothetical protein.
  
  
 0.607
EHA62255.1
TIGRFAM: Competence-induced protein CinA; CinA, C-terminal; PFAM: CinA, C-terminal; Molybdopterin binding; KEGG: pmf:P9303_24701 molybdenum cofactor biosynthesis protein; SMART: Molybdopterin binding.
     
 0.577
EHA61869.1
PFAM: Type II/III secretion system; NolW-like; KEGG: pmt:PMT2098 general (type II) secretion pathway protein D precursor; Belongs to the bacterial secretin family.
 
  
 0.561
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.