| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EHA59101.1 | EHA59175.1 | Syn8016DRAFT_2824 | Syn8016DRAFT_2898 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, clamp; DNA mismatch repair protein MutS, core; SMART: DNA mismatch repair protein MutS, C-terminal. | 0.906 |
| EHA59101.1 | EHA59176.1 | Syn8016DRAFT_2824 | Syn8016DRAFT_2899 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: DNA mismatch repair protein MutS-like, N-terminal; DNA mismatch repair protein MutS, connector; DNA mismatch repair protein MutS, core; KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS. | 0.906 |
| EHA59101.1 | EHA60243.1 | Syn8016DRAFT_2824 | Syn8016DRAFT_2625 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | TIGRFAM: DNA helicase, ATP-dependent, RecQ type; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; KEGG: pmf:P9303_21731 superfamily II DNA helicase; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal. | 0.942 |
| EHA59101.1 | EHA63469.1 | Syn8016DRAFT_2824 | Syn8016DRAFT_0510 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: mxa:MXAN_6073 hypothetical protein. | 0.551 |
| EHA59101.1 | EHA63470.1 | Syn8016DRAFT_2824 | Syn8016DRAFT_0511 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: DNA ligase, ATP-dependent, central; DNA ligase, ATP-dependent, C-terminal; KEGG: pcu:pc0950 ATP-dependent DNA ligase. | 0.913 |
| EHA59101.1 | EHA63784.1 | Syn8016DRAFT_2824 | Syn8016DRAFT_0825 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: DNA ligase, ATP-dependent, central; KEGG: bpm:BURPS1710b_1648 PBCV-1 DNA ligase. | 0.913 |
| EHA59101.1 | polA | Syn8016DRAFT_2824 | Syn8016DRAFT_0084 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.994 |
| EHA59101.1 | recA | Syn8016DRAFT_2824 | Syn8016DRAFT_2700 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.941 |
| EHA59101.1 | topA | Syn8016DRAFT_2824 | Syn8016DRAFT_1355 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.708 |
| EHA59175.1 | EHA59101.1 | Syn8016DRAFT_2898 | Syn8016DRAFT_2824 | KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, clamp; DNA mismatch repair protein MutS, core; SMART: DNA mismatch repair protein MutS, C-terminal. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.906 |
| EHA59175.1 | EHA59176.1 | Syn8016DRAFT_2898 | Syn8016DRAFT_2899 | KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, clamp; DNA mismatch repair protein MutS, core; SMART: DNA mismatch repair protein MutS, C-terminal. | PFAM: DNA mismatch repair protein MutS-like, N-terminal; DNA mismatch repair protein MutS, connector; DNA mismatch repair protein MutS, core; KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS. | 0.990 |
| EHA59175.1 | EHA60243.1 | Syn8016DRAFT_2898 | Syn8016DRAFT_2625 | KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, clamp; DNA mismatch repair protein MutS, core; SMART: DNA mismatch repair protein MutS, C-terminal. | TIGRFAM: DNA helicase, ATP-dependent, RecQ type; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; KEGG: pmf:P9303_21731 superfamily II DNA helicase; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal. | 0.741 |
| EHA59175.1 | EHA63469.1 | Syn8016DRAFT_2898 | Syn8016DRAFT_0510 | KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, clamp; DNA mismatch repair protein MutS, core; SMART: DNA mismatch repair protein MutS, C-terminal. | KEGG: mxa:MXAN_6073 hypothetical protein. | 0.590 |
| EHA59175.1 | EHA63470.1 | Syn8016DRAFT_2898 | Syn8016DRAFT_0511 | KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, clamp; DNA mismatch repair protein MutS, core; SMART: DNA mismatch repair protein MutS, C-terminal. | PFAM: DNA ligase, ATP-dependent, central; DNA ligase, ATP-dependent, C-terminal; KEGG: pcu:pc0950 ATP-dependent DNA ligase. | 0.719 |
| EHA59175.1 | EHA63784.1 | Syn8016DRAFT_2898 | Syn8016DRAFT_0825 | KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, clamp; DNA mismatch repair protein MutS, core; SMART: DNA mismatch repair protein MutS, C-terminal. | PFAM: DNA ligase, ATP-dependent, central; KEGG: bpm:BURPS1710b_1648 PBCV-1 DNA ligase. | 0.719 |
| EHA59175.1 | mutS2 | Syn8016DRAFT_2898 | Syn8016DRAFT_2263 | KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, clamp; DNA mismatch repair protein MutS, core; SMART: DNA mismatch repair protein MutS, C-terminal. | MutS2 protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. | 0.735 |
| EHA59175.1 | polA | Syn8016DRAFT_2898 | Syn8016DRAFT_0084 | KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, clamp; DNA mismatch repair protein MutS, core; SMART: DNA mismatch repair protein MutS, C-terminal. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.931 |
| EHA59175.1 | recA | Syn8016DRAFT_2898 | Syn8016DRAFT_2700 | KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, clamp; DNA mismatch repair protein MutS, core; SMART: DNA mismatch repair protein MutS, C-terminal. | Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.651 |
| EHA59175.1 | topA | Syn8016DRAFT_2898 | Syn8016DRAFT_1355 | KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, clamp; DNA mismatch repair protein MutS, core; SMART: DNA mismatch repair protein MutS, C-terminal. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.712 |
| EHA59176.1 | EHA59101.1 | Syn8016DRAFT_2899 | Syn8016DRAFT_2824 | PFAM: DNA mismatch repair protein MutS-like, N-terminal; DNA mismatch repair protein MutS, connector; DNA mismatch repair protein MutS, core; KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.906 |
