STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadK-2Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (302 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.928
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
  
0.895
EHA60388.1
PFAM: Cytidylyltransferase; KEGG: pmt:PMT1460 nicotinic acid mononucleotide adenylyltransferase; Belongs to the NadD family.
  
 
 0.886
EHA63031.1
KEGG: pmt:PMT1165 putative nicotinamide nucleotide transhydrogenase, subunit alpha 2 (A2).
     
 0.877
EHA63030.1
NAD(P)(+) transhydrogenase (AB-specific); KEGG: pmf:P9303_08601 putative nicotinamide nucleotide transhydrogenase, subunit alpha 1 (A1); PFAM: Alanine dehydrogenase/PNT, C-terminal; Alanine dehydrogenase/PNT, N-terminal.
     
 0.873
EHA63032.1
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.867
EHA58620.1
Transcriptional regulator, winged helix family; KEGG: amr:AM1_0794 two-component transcriptional regulator; PFAM: Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, C-terminal.
    
  0.828
EHA58621.1
PFAM: Protein of unknown function DUF192; KEGG: pmf:P9303_19321 hypothetical protein.
       0.786
EHA63101.1
PFAM: Acid phosphatase/vanadium-dependent haloperoxidase-related; KEGG: pmf:P9303_09341 hypothetical protein.
    
  0.730
EHA62454.1
PFAM: SNARE associated Golgi protein; KEGG: pmf:P9303_01771 DedA family alkaline phosphatase-like protein.
    
  0.730
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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