| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XM1_1140 | folE | XM1_1140 | XM1_0397 | 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.977 |
| XM1_3360 | XM1_3723 | XM1_3360 | XM1_3723 | Dihydroneopterin aldolase; Function of strongly homologous gene; enzyme. | Tetrahydromethanopterin S-methyltransferase (fragment); Function of strongly homologous gene; enzyme. | 0.882 |
| XM1_3360 | folE | XM1_3360 | XM1_0397 | Dihydroneopterin aldolase; Function of strongly homologous gene; enzyme. | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.941 |
| XM1_3360 | folK | XM1_3360 | XM1_3358 | Dihydroneopterin aldolase; Function of strongly homologous gene; enzyme. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.996 |
| XM1_3360 | folP | XM1_3360 | XM1_4116 | Dihydroneopterin aldolase; Function of strongly homologous gene; enzyme. | Dihydropteroate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.992 |
| XM1_3360 | ribB | XM1_3360 | XM1_3125 | Dihydroneopterin aldolase; Function of strongly homologous gene; enzyme. | Riboflavin biosynthesis protein RibBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.501 |
| XM1_3723 | XM1_3360 | XM1_3723 | XM1_3360 | Tetrahydromethanopterin S-methyltransferase (fragment); Function of strongly homologous gene; enzyme. | Dihydroneopterin aldolase; Function of strongly homologous gene; enzyme. | 0.882 |
| XM1_3723 | folE | XM1_3723 | XM1_0397 | Tetrahydromethanopterin S-methyltransferase (fragment); Function of strongly homologous gene; enzyme. | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.882 |
| XM1_3723 | folK | XM1_3723 | XM1_3358 | Tetrahydromethanopterin S-methyltransferase (fragment); Function of strongly homologous gene; enzyme. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.882 |
| XM1_3723 | ribB | XM1_3723 | XM1_3125 | Tetrahydromethanopterin S-methyltransferase (fragment); Function of strongly homologous gene; enzyme. | Riboflavin biosynthesis protein RibBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.457 |
| folE | XM1_1140 | XM1_0397 | XM1_1140 | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.977 |
| folE | XM1_3360 | XM1_0397 | XM1_3360 | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Dihydroneopterin aldolase; Function of strongly homologous gene; enzyme. | 0.941 |
| folE | XM1_3723 | XM1_0397 | XM1_3723 | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Tetrahydromethanopterin S-methyltransferase (fragment); Function of strongly homologous gene; enzyme. | 0.882 |
| folE | folK | XM1_0397 | XM1_3358 | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.997 |
| folE | folP | XM1_0397 | XM1_4116 | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Dihydropteroate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.968 |
| folE | mazG | XM1_0397 | XM1_3186 | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Nucleoside triphosphate pyrophosphohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.836 |
| folE | moaA | XM1_0397 | XM1_1049 | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Cyclic pyranopterin monophosphate synthase(Molybdenum cofactor biosynthesis protein A,1-328); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.910 |
| folE | ndk | XM1_0397 | XM1_4418 | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Nucleoside diphosphate kinase ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.847 |
| folE | ribA | XM1_0397 | XM1_0869 | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.931 |
| folE | ribB | XM1_0397 | XM1_3125 | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Riboflavin biosynthesis protein RibBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.948 |