| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| argS | guaA | XM1_3293 | XM1_4635 | arginyl-tRNA synthetase; Function of strongly homologous gene; enzyme. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.985 |
| argS | guaB | XM1_3293 | XM1_1579 | arginyl-tRNA synthetase; Function of strongly homologous gene; enzyme. | IMP dehydrogenase(Inosine-5'-monophosphate dehydrogenase,3-478); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.479 |
| argS | lepA | XM1_3293 | XM1_1493 | arginyl-tRNA synthetase; Function of strongly homologous gene; enzyme. | GTP-binding membrane protein(Elongation factor, Elongation factor 4,6-597); Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.695 |
| argS | pheT | XM1_3293 | XM1_0527 | arginyl-tRNA synthetase; Function of strongly homologous gene; enzyme. | Phenylalanine--tRNA ligase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.912 |
| argS | prfA | XM1_3293 | XM1_3823 | arginyl-tRNA synthetase; Function of strongly homologous gene; enzyme. | Peptide chain release factor RF-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.663 |
| argS | rpsG | XM1_3293 | XM1_2085 | arginyl-tRNA synthetase; Function of strongly homologous gene; enzyme. | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.848 |
| argS | rpsI | XM1_3293 | XM1_4412 | arginyl-tRNA synthetase; Function of strongly homologous gene; enzyme. | 30S ribosomal subunit protein S9; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the universal ribosomal protein uS9 family. | 0.423 |
| argS | ychF | XM1_3293 | XM1_0693 | arginyl-tRNA synthetase; Function of strongly homologous gene; enzyme. | Putative GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.786 |
| guaA | argS | XM1_4635 | XM1_3293 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | arginyl-tRNA synthetase; Function of strongly homologous gene; enzyme. | 0.985 |
| guaA | guaB | XM1_4635 | XM1_1579 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | IMP dehydrogenase(Inosine-5'-monophosphate dehydrogenase,3-478); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA | lepA | XM1_4635 | XM1_1493 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | GTP-binding membrane protein(Elongation factor, Elongation factor 4,6-597); Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.623 |
| guaA | pheT | XM1_4635 | XM1_0527 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Phenylalanine--tRNA ligase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.961 |
| guaA | pth | XM1_4635 | XM1_0692 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.687 |
| guaA | rplY | XM1_4635 | XM1_0691 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.526 |
| guaA | rpsG | XM1_4635 | XM1_2085 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.853 |
| guaA | rpsI | XM1_4635 | XM1_4412 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 30S ribosomal subunit protein S9; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the universal ribosomal protein uS9 family. | 0.610 |
| guaA | ychF | XM1_4635 | XM1_0693 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Putative GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.792 |
| guaB | argS | XM1_1579 | XM1_3293 | IMP dehydrogenase(Inosine-5'-monophosphate dehydrogenase,3-478); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | arginyl-tRNA synthetase; Function of strongly homologous gene; enzyme. | 0.479 |
| guaB | guaA | XM1_1579 | XM1_4635 | IMP dehydrogenase(Inosine-5'-monophosphate dehydrogenase,3-478); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.999 |
| guaB | lepA | XM1_1579 | XM1_1493 | IMP dehydrogenase(Inosine-5'-monophosphate dehydrogenase,3-478); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GTP-binding membrane protein(Elongation factor, Elongation factor 4,6-597); Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.586 |