| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XM1_0701 | XM1_0703 | XM1_0701 | XM1_0703 | Homologs of previously reported genes of unknown function. | Putative Cytochrome C4; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.784 |
| XM1_0701 | cobN | XM1_0701 | XM1_0706 | Homologs of previously reported genes of unknown function. | Aerobic cobaltochelatase subunit CobN; Function of strongly homologous gene; enzyme. | 0.773 |
| XM1_0701 | gcp | XM1_0701 | XM1_0698 | Homologs of previously reported genes of unknown function. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.589 |
| XM1_0701 | greB | XM1_0701 | XM1_0697 | Homologs of previously reported genes of unknown function. | Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. | 0.563 |
| XM1_0701 | hemC | XM1_0701 | XM1_0699 | Homologs of previously reported genes of unknown function. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.788 |
| XM1_0701 | hemD | XM1_0701 | XM1_0700 | Homologs of previously reported genes of unknown function. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.951 |
| XM1_0703 | XM1_0701 | XM1_0703 | XM1_0701 | Putative Cytochrome C4; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Homologs of previously reported genes of unknown function. | 0.784 |
| XM1_0703 | cobN | XM1_0703 | XM1_0706 | Putative Cytochrome C4; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Aerobic cobaltochelatase subunit CobN; Function of strongly homologous gene; enzyme. | 0.773 |
| XM1_0703 | gcp | XM1_0703 | XM1_0698 | Putative Cytochrome C4; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.563 |
| XM1_0703 | greB | XM1_0703 | XM1_0697 | Putative Cytochrome C4; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. | 0.641 |
| XM1_0703 | hemC | XM1_0703 | XM1_0699 | Putative Cytochrome C4; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.793 |
| XM1_0703 | hemD | XM1_0703 | XM1_0700 | Putative Cytochrome C4; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.784 |
| cobN | XM1_0701 | XM1_0706 | XM1_0701 | Aerobic cobaltochelatase subunit CobN; Function of strongly homologous gene; enzyme. | Homologs of previously reported genes of unknown function. | 0.773 |
| cobN | XM1_0703 | XM1_0706 | XM1_0703 | Aerobic cobaltochelatase subunit CobN; Function of strongly homologous gene; enzyme. | Putative Cytochrome C4; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.773 |
| cobN | gcp | XM1_0706 | XM1_0698 | Aerobic cobaltochelatase subunit CobN; Function of strongly homologous gene; enzyme. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.564 |
| cobN | greB | XM1_0706 | XM1_0697 | Aerobic cobaltochelatase subunit CobN; Function of strongly homologous gene; enzyme. | Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. | 0.573 |
| cobN | hemC | XM1_0706 | XM1_0699 | Aerobic cobaltochelatase subunit CobN; Function of strongly homologous gene; enzyme. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.850 |
| cobN | hemD | XM1_0706 | XM1_0700 | Aerobic cobaltochelatase subunit CobN; Function of strongly homologous gene; enzyme. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.806 |
| gcp | XM1_0701 | XM1_0698 | XM1_0701 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Homologs of previously reported genes of unknown function. | 0.589 |
| gcp | XM1_0703 | XM1_0698 | XM1_0703 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Putative Cytochrome C4; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.563 |