| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XM1_0749 | birA | XM1_0749 | XM1_3583 | Putative peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Biotin--[acetyl-CoA-carboxylase] ligase; Function of strongly homologous gene; enzyme. | 0.539 |
| XM1_0749 | guaA | XM1_0749 | XM1_4635 | Putative peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.456 |
| XM1_0749 | tadA | XM1_0749 | XM1_1126 | Putative peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.728 |
| XM1_0749 | truA | XM1_0749 | XM1_1130 | Putative peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | tRNA pseudouridine synthase A(Pseudouridine synthase, catalytic domain,1-247); Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.403 |
| birA | XM1_0749 | XM1_3583 | XM1_0749 | Biotin--[acetyl-CoA-carboxylase] ligase; Function of strongly homologous gene; enzyme. | Putative peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.539 |
| birA | guaA | XM1_3583 | XM1_4635 | Biotin--[acetyl-CoA-carboxylase] ligase; Function of strongly homologous gene; enzyme. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.522 |
| birA | guaB | XM1_3583 | XM1_1579 | Biotin--[acetyl-CoA-carboxylase] ligase; Function of strongly homologous gene; enzyme. | IMP dehydrogenase(Inosine-5'-monophosphate dehydrogenase,3-478); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.539 |
| birA | ribB | XM1_3583 | XM1_3125 | Biotin--[acetyl-CoA-carboxylase] ligase; Function of strongly homologous gene; enzyme. | Riboflavin biosynthesis protein RibBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.563 |
| birA | tadA | XM1_3583 | XM1_1126 | Biotin--[acetyl-CoA-carboxylase] ligase; Function of strongly homologous gene; enzyme. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.592 |
| cbbY | tadA | XM1_1798 | XM1_1126 | Haloacid dehalogenase-like hydrolase, protein CbbY, plasmid(HAD-like domain,1-211); Function of strongly homologous gene; enzyme. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.678 |
| guaA | XM1_0749 | XM1_4635 | XM1_0749 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Putative peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.456 |
| guaA | birA | XM1_4635 | XM1_3583 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Biotin--[acetyl-CoA-carboxylase] ligase; Function of strongly homologous gene; enzyme. | 0.522 |
| guaA | guaB | XM1_4635 | XM1_1579 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | IMP dehydrogenase(Inosine-5'-monophosphate dehydrogenase,3-478); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA | ribB | XM1_4635 | XM1_3125 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Riboflavin biosynthesis protein RibBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.779 |
| guaA | tadA | XM1_4635 | XM1_1126 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.691 |
| guaA | tilS | XM1_4635 | XM1_4118 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.566 |
| guaB | birA | XM1_1579 | XM1_3583 | IMP dehydrogenase(Inosine-5'-monophosphate dehydrogenase,3-478); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Biotin--[acetyl-CoA-carboxylase] ligase; Function of strongly homologous gene; enzyme. | 0.539 |
| guaB | guaA | XM1_1579 | XM1_4635 | IMP dehydrogenase(Inosine-5'-monophosphate dehydrogenase,3-478); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.999 |
| guaB | ribB | XM1_1579 | XM1_3125 | IMP dehydrogenase(Inosine-5'-monophosphate dehydrogenase,3-478); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Riboflavin biosynthesis protein RibBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.920 |
| guaB | tadA | XM1_1579 | XM1_1126 | IMP dehydrogenase(Inosine-5'-monophosphate dehydrogenase,3-478); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.593 |