STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pycAPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1154 aa)    
Predicted Functional Partners:
acoB
Acetoin dehydrogenase E1 component (TPP-dependent beta subunit); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.963
ytsJ
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.957
gltA
Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.
  
 0.957
dme
NAD-dependent malic enzyme; Function of strongly homologous gene; putative enzyme.
   
 0.957
mdh
Malate dehydrogenase(Malate dehydrogenase, type 3,3-313); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.954
pyk
Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family.
   
 0.952
ydbK
Putative 2-oxoacid-flavodoxin fused oxidoreductase:conserved protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 0.951
pckG
Phosphoenolpyruvate carboxykinase pckG; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
   
 
 0.939
XM1_2900
Putative 2-oxoglutarate ferredoxin oxidoreductase alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.938
ppdK
Pyruvate phosphate dikinase; Function of strongly homologous gene; enzyme; Belongs to the PEP-utilizing enzyme family.
  
 
 0.921
Your Current Organism:
Magnetospirillum sp. XM1
NCBI taxonomy Id: 1663591
Other names: M. sp. XM-1, Magnetospirillum sp. XM-1
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