STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccmGCytochrome c biogenesis protein CcmG, thiol:disulfide interchange protein DsbE; Function of strongly homologous gene; membrane component. (181 aa)    
Predicted Functional Partners:
ccmF
Heme lyase, CcmF subunit(Cytochrome c-type biogenesis protein Ccm,53-645) Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.987
XM1_1190
Cytochrome c-type biogenesis protein CcmH; Function of strongly homologous gene; membrane component.
 
  
 0.985
cycL
Cytochrome c-type biogenesis protein cycL; Possible subunit of a heme lyase.
 
  
 0.981
ccmE
Periplasmic heme chaperone(CcmE/CycJ protein,2-129) Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
  
 0.970
ccmC
Heme exporter subunit; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
  
 0.970
XM1_2525
Putative Cytochrome c-type biogenesis protein CcmF (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.952
ccmB
Heme exporter subunit; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
  
 0.858
XM1_4258
Putative fused thiol:disulfide interchange protein: activator of DsbC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.825
ccmA
Cytochrome c biogenesis ATP-binding export protein CcmA(ABC transporter, haem export, CcmA,11-211); Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
   
 0.801
XM1_1195
Conserved protein of unknown function; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
  
  
 0.797
Your Current Organism:
Magnetospirillum sp. XM1
NCBI taxonomy Id: 1663591
Other names: M. sp. XM-1, Magnetospirillum sp. XM-1
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