STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccrMIMModification methylase CcrMI(DNA methylase N-4/N-6,25-246); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the N(4)/N(6)-methyltransferase family. (358 aa)    
Predicted Functional Partners:
XM1_1336
Homologs of previously reported genes of unknown function.
       0.784
lexA
Putative transcriptional repressor of the SOS regulon; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
    
 0.721
rnhB
Ribonuclease HII, degrades RNA of DNA-RNA hybrids (Ribonuclease H-like domain; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.562
cobT-2
Aerobic cobaltochelatase subunit CobT(Cobalt chelatase, CobT subunit,19-618); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
     0.526
XM1_0016
Putative transcriptional regulator, AbrB family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
 
  
 0.524
cobS-2
Aerobic cobaltochelatase subunit CobS; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
    0.523
recA
DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
 
   
 0.487
sucD
succinyl-CoA synthetase alpha chain(Succinyl-CoA ligase, alpha subunit,4-289); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
    0.481
sucC
succinyl-CoA synthetase, beta subunit(Succinyl-CoA synthetase, beta subunit,1-398); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
    0.481
XM1_0200
Signal transduction histidine kinase; Function of strongly homologous gene; enzyme.
 
  
 0.475
Your Current Organism:
Magnetospirillum sp. XM1
NCBI taxonomy Id: 1663591
Other names: M. sp. XM-1, Magnetospirillum sp. XM-1
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