STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdhDSuccinate dehydrogenase / fumarate reductase, membrane anchor subunit; Function of strongly homologous gene; membrane component. (126 aa)    
Predicted Functional Partners:
sdhB
Succinate dehydrogenase / fumarate reductase, iron-sulfur subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier.
 
 0.999
sdhA
Succinate dehydrogenase flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.999
sdhC
Succinate dehydrogenase / fumarate reductase, cytochrome b subunit; Function of strongly homologous gene; enzyme.
 
 0.999
sucC
succinyl-CoA synthetase, beta subunit(Succinyl-CoA synthetase, beta subunit,1-398); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.991
fumA
Fumarate hydratase (fumarase A), aerobic Class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.984
sucD
succinyl-CoA synthetase alpha chain(Succinyl-CoA ligase, alpha subunit,4-289); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.958
fumC
Fumarate hydratase (fumarase C),aerobic Class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.925
gabD
Succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aldehyde dehydrogenase family.
   
 
 0.909
mamF-2
Magnetosome protein MamF; Function of strongly homologous gene; enzyme.
     
  0.900
sucA
2-oxoglutarate dehydrogenase E1 component; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.879
Your Current Organism:
Magnetospirillum sp. XM1
NCBI taxonomy Id: 1663591
Other names: M. sp. XM-1, Magnetospirillum sp. XM-1
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