| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XM1_3510 | cobB-2 | XM1_3510 | XM1_1776 | Putative NADH pyrophosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Deacetylase of acetyl-CoA synthetase, NAD-dependent(Sirtuin family,7-234); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the sirtuin family. Class III subfamily. | 0.912 |
| XM1_3510 | mazG | XM1_3510 | XM1_3186 | Putative NADH pyrophosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Nucleoside triphosphate pyrophosphohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.913 |
| XM1_3510 | nadD | XM1_3510 | XM1_0298 | Putative NADH pyrophosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative nicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.906 |
| XM1_3510 | nadE | XM1_3510 | XM1_1865 | Putative NADH pyrophosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.914 |
| XM1_3510 | nadK | XM1_3510 | XM1_1057 | Putative NADH pyrophosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.904 |
| XM1_3510 | pntA | XM1_3510 | XM1_3674 | Putative NADH pyrophosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Pyridine nucleotide transhydrogenase, alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.900 |
| XM1_3510 | pntB | XM1_3510 | XM1_3673 | Putative NADH pyrophosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Pyridine nucleotide transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.900 |
| cobB-2 | XM1_3510 | XM1_1776 | XM1_3510 | Deacetylase of acetyl-CoA synthetase, NAD-dependent(Sirtuin family,7-234); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the sirtuin family. Class III subfamily. | Putative NADH pyrophosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.912 |
| cobB-2 | mazG | XM1_1776 | XM1_3186 | Deacetylase of acetyl-CoA synthetase, NAD-dependent(Sirtuin family,7-234); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the sirtuin family. Class III subfamily. | Nucleoside triphosphate pyrophosphohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.902 |
| cobB-2 | nadD | XM1_1776 | XM1_0298 | Deacetylase of acetyl-CoA synthetase, NAD-dependent(Sirtuin family,7-234); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the sirtuin family. Class III subfamily. | Putative nicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.943 |
| cobB-2 | nadE | XM1_1776 | XM1_1865 | Deacetylase of acetyl-CoA synthetase, NAD-dependent(Sirtuin family,7-234); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the sirtuin family. Class III subfamily. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.961 |
| cobB-2 | nadK | XM1_1776 | XM1_1057 | Deacetylase of acetyl-CoA synthetase, NAD-dependent(Sirtuin family,7-234); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the sirtuin family. Class III subfamily. | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.920 |
| cobB-2 | pntA | XM1_1776 | XM1_3674 | Deacetylase of acetyl-CoA synthetase, NAD-dependent(Sirtuin family,7-234); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the sirtuin family. Class III subfamily. | Pyridine nucleotide transhydrogenase, alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.910 |
| cobB-2 | pntB | XM1_1776 | XM1_3673 | Deacetylase of acetyl-CoA synthetase, NAD-dependent(Sirtuin family,7-234); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the sirtuin family. Class III subfamily. | Pyridine nucleotide transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.902 |
| gltX | guaA | XM1_1866 | XM1_4635 | Glutamate--tRNA ligase 1(Glutamate-tRNA ligase, class Ib, bacterial/mitochondria,5-326); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.723 |
| gltX | nadE | XM1_1866 | XM1_1865 | Glutamate--tRNA ligase 1(Glutamate-tRNA ligase, class Ib, bacterial/mitochondria,5-326); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.828 |
| gltX | ribD | XM1_1866 | XM1_3123 | Glutamate--tRNA ligase 1(Glutamate-tRNA ligase, class Ib, bacterial/mitochondria,5-326); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.529 |
| guaA | gltX | XM1_4635 | XM1_1866 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Glutamate--tRNA ligase 1(Glutamate-tRNA ligase, class Ib, bacterial/mitochondria,5-326); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.723 |
| guaA | mazG | XM1_4635 | XM1_3186 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Nucleoside triphosphate pyrophosphohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.903 |
| guaA | nadE | XM1_4635 | XM1_1865 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.751 |