| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XM1_1947 | XM1_1948 | XM1_1947 | XM1_1948 | Homologs of previously reported genes of unknown function. | TRAP-type transport system periplasmic protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.784 |
| XM1_1947 | XM1_1949 | XM1_1947 | XM1_1949 | Homologs of previously reported genes of unknown function. | NitT/TauT family transport system ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.527 |
| XM1_1947 | XM1_1950 | XM1_1947 | XM1_1950 | Homologs of previously reported genes of unknown function. | Uncharacterized protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.517 |
| XM1_1948 | XM1_1947 | XM1_1948 | XM1_1947 | TRAP-type transport system periplasmic protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Homologs of previously reported genes of unknown function. | 0.784 |
| XM1_1948 | XM1_1949 | XM1_1948 | XM1_1949 | TRAP-type transport system periplasmic protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | NitT/TauT family transport system ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.527 |
| XM1_1948 | XM1_1950 | XM1_1948 | XM1_1950 | TRAP-type transport system periplasmic protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Uncharacterized protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.517 |
| XM1_1949 | XM1_1947 | XM1_1949 | XM1_1947 | NitT/TauT family transport system ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Homologs of previously reported genes of unknown function. | 0.527 |
| XM1_1949 | XM1_1948 | XM1_1949 | XM1_1948 | NitT/TauT family transport system ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | TRAP-type transport system periplasmic protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.527 |
| XM1_1949 | XM1_1950 | XM1_1949 | XM1_1950 | NitT/TauT family transport system ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Uncharacterized protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.977 |
| XM1_1949 | folA | XM1_1949 | XM1_1951 | NitT/TauT family transport system ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Dihydrofolate reductase(Dihydrofolate reductase-like domain,3-162) Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.527 |
| XM1_1949 | thyA | XM1_1949 | XM1_1952 | NitT/TauT family transport system ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Thymidylate synthase (TS) (TSase); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.514 |
| XM1_1950 | XM1_1947 | XM1_1950 | XM1_1947 | Uncharacterized protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Homologs of previously reported genes of unknown function. | 0.517 |
| XM1_1950 | XM1_1948 | XM1_1950 | XM1_1948 | Uncharacterized protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | TRAP-type transport system periplasmic protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.517 |
| XM1_1950 | XM1_1949 | XM1_1950 | XM1_1949 | Uncharacterized protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | NitT/TauT family transport system ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.977 |
| XM1_1950 | folA | XM1_1950 | XM1_1951 | Uncharacterized protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Dihydrofolate reductase(Dihydrofolate reductase-like domain,3-162) Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.536 |
| XM1_1950 | thyA | XM1_1950 | XM1_1952 | Uncharacterized protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Thymidylate synthase (TS) (TSase); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.524 |
| folA | XM1_1949 | XM1_1951 | XM1_1949 | Dihydrofolate reductase(Dihydrofolate reductase-like domain,3-162) Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | NitT/TauT family transport system ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.527 |
| folA | XM1_1950 | XM1_1951 | XM1_1950 | Dihydrofolate reductase(Dihydrofolate reductase-like domain,3-162) Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Uncharacterized protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.536 |
| folA | thyA | XM1_1951 | XM1_1952 | Dihydrofolate reductase(Dihydrofolate reductase-like domain,3-162) Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Thymidylate synthase (TS) (TSase); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.999 |
| thyA | XM1_1949 | XM1_1952 | XM1_1949 | Thymidylate synthase (TS) (TSase); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | NitT/TauT family transport system ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.514 |