| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XM1_0372 | XM1_1767 | XM1_0372 | XM1_1767 | Putative phosphotransferase related to Ser/Thr protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative cell wall amidase and lipoprotein (N-acetylmuramoyl-L-alanine amidase domain,4-163); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.492 |
| XM1_0372 | ampG | XM1_0372 | XM1_0785 | Putative phosphotransferase related to Ser/Thr protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Permease of the major facilitator superfamily, AmpG-like; Function of homologous gene experimentally demonstrated in an other organism; transporter. | 0.503 |
| XM1_0372 | anmK | XM1_0372 | XM1_2203 | Putative phosphotransferase related to Ser/Thr protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.413 |
| XM1_0372 | gcaD | XM1_0372 | XM1_1904 | Putative phosphotransferase related to Ser/Thr protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.918 |
| XM1_0372 | nagZ | XM1_0372 | XM1_3291 | Putative phosphotransferase related to Ser/Thr protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Beta-N-acetylhexosaminidase; Function of strongly homologous gene; enzyme. | 0.958 |
| XM1_1767 | XM1_0372 | XM1_1767 | XM1_0372 | Putative cell wall amidase and lipoprotein (N-acetylmuramoyl-L-alanine amidase domain,4-163); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative phosphotransferase related to Ser/Thr protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.492 |
| XM1_1767 | ampG | XM1_1767 | XM1_0785 | Putative cell wall amidase and lipoprotein (N-acetylmuramoyl-L-alanine amidase domain,4-163); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Permease of the major facilitator superfamily, AmpG-like; Function of homologous gene experimentally demonstrated in an other organism; transporter. | 0.525 |
| XM1_1767 | anmK | XM1_1767 | XM1_2203 | Putative cell wall amidase and lipoprotein (N-acetylmuramoyl-L-alanine amidase domain,4-163); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.499 |
| XM1_1767 | nagZ | XM1_1767 | XM1_3291 | Putative cell wall amidase and lipoprotein (N-acetylmuramoyl-L-alanine amidase domain,4-163); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Beta-N-acetylhexosaminidase; Function of strongly homologous gene; enzyme. | 0.772 |
| XM1_2204 | anmK | XM1_2204 | XM1_2203 | Homologs of previously reported genes of unknown function. | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.754 |
| XM1_2204 | tyrS | XM1_2204 | XM1_2202 | Homologs of previously reported genes of unknown function. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.543 |
| ampG | XM1_0372 | XM1_0785 | XM1_0372 | Permease of the major facilitator superfamily, AmpG-like; Function of homologous gene experimentally demonstrated in an other organism; transporter. | Putative phosphotransferase related to Ser/Thr protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.503 |
| ampG | XM1_1767 | XM1_0785 | XM1_1767 | Permease of the major facilitator superfamily, AmpG-like; Function of homologous gene experimentally demonstrated in an other organism; transporter. | Putative cell wall amidase and lipoprotein (N-acetylmuramoyl-L-alanine amidase domain,4-163); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.525 |
| ampG | anmK | XM1_0785 | XM1_2203 | Permease of the major facilitator superfamily, AmpG-like; Function of homologous gene experimentally demonstrated in an other organism; transporter. | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.463 |
| ampG | nagZ | XM1_0785 | XM1_3291 | Permease of the major facilitator superfamily, AmpG-like; Function of homologous gene experimentally demonstrated in an other organism; transporter. | Beta-N-acetylhexosaminidase; Function of strongly homologous gene; enzyme. | 0.586 |
| anmK | XM1_0372 | XM1_2203 | XM1_0372 | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Putative phosphotransferase related to Ser/Thr protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.413 |
| anmK | XM1_1767 | XM1_2203 | XM1_1767 | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Putative cell wall amidase and lipoprotein (N-acetylmuramoyl-L-alanine amidase domain,4-163); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.499 |
| anmK | XM1_2204 | XM1_2203 | XM1_2204 | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Homologs of previously reported genes of unknown function. | 0.754 |
| anmK | ampG | XM1_2203 | XM1_0785 | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Permease of the major facilitator superfamily, AmpG-like; Function of homologous gene experimentally demonstrated in an other organism; transporter. | 0.463 |
| anmK | gcaD | XM1_2203 | XM1_1904 | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.402 |