STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iscRDNA-binding transcriptional repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator. (151 aa)    
Predicted Functional Partners:
nifS
Cysteine desulfurase; Function of strongly homologous gene; enzyme.
  
 0.947
iscS
Cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
 0.858
XM1_2206
Serine acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.849
hscB
Co-chaperone protein HscB homolog; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
  
  
 0.784
iscU
Scaffold protein;iron-binding protein believed to be involved in Fe-S protein formation or repair; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
  
 0.776
iscA
FeS cluster assembly protein; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the HesB/IscA family.
  
  
 0.711
XM1_2783
Putative Fe-S cluster formation NifU-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.660
fdx
[2Fe-2S] ferredoxin; Function of homologous gene experimentally demonstrated in an other organism; carrier.
  
  
 0.634
XM1_2205
Putative alpha/beta superfamily hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.564
fdx-2
4Fe-4S ferredoxin-type protein; Function of strongly homologous gene; carrier.
  
  
 0.564
Your Current Organism:
Magnetospirillum sp. XM1
NCBI taxonomy Id: 1663591
Other names: M. sp. XM-1, Magnetospirillum sp. XM-1
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