| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XM1_2744 | hupB-4 | XM1_2744 | XM1_2743 | Putative Acyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | HU, DNA-binding transcriptional regulator, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family. | 0.445 |
| XM1_4047 | hupB-4 | XM1_4047 | XM1_2743 | Conserved protein of unknown function (Chromosomal replication initiator, DnaA C-terminal 2-93); Homologs of previously reported genes of unknown function. | HU, DNA-binding transcriptional regulator, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family. | 0.443 |
| dnaA | hupB-4 | XM1_0002 | XM1_2743 | Chromosomal replication initiator protein DnaA, DNA-binding transcriptional dual regulator; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | HU, DNA-binding transcriptional regulator, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family. | 0.443 |
| hupB-4 | XM1_2744 | XM1_2743 | XM1_2744 | HU, DNA-binding transcriptional regulator, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family. | Putative Acyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.445 |
| hupB-4 | XM1_4047 | XM1_2743 | XM1_4047 | HU, DNA-binding transcriptional regulator, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family. | Conserved protein of unknown function (Chromosomal replication initiator, DnaA C-terminal 2-93); Homologs of previously reported genes of unknown function. | 0.443 |
| hupB-4 | dnaA | XM1_2743 | XM1_0002 | HU, DNA-binding transcriptional regulator, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family. | Chromosomal replication initiator protein DnaA, DNA-binding transcriptional dual regulator; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.443 |
| hupB-4 | ihfA | XM1_2743 | XM1_3138 | HU, DNA-binding transcriptional regulator, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family. | Integration host factor (IHF), DNA-binding protein, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.584 |
| hupB-4 | rplL | XM1_2743 | XM1_2078 | HU, DNA-binding transcriptional regulator, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family. | 50S ribosomal subunit protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.404 |
| hupB-4 | rplS | XM1_2743 | XM1_0280 | HU, DNA-binding transcriptional regulator, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family. | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.421 |
| hupB-4 | rpmF | XM1_2743 | XM1_3135 | HU, DNA-binding transcriptional regulator, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family. | 50S ribosomal subunit protein L32; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL32 family. | 0.409 |
| hupB-4 | rpsO | XM1_2743 | XM1_0334 | HU, DNA-binding transcriptional regulator, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family. | 30S ribosomal subunit protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.431 |
| hupB-4 | rpsT | XM1_2743 | XM1_4792 | HU, DNA-binding transcriptional regulator, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family. | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.454 |
| ihfA | hupB-4 | XM1_3138 | XM1_2743 | Integration host factor (IHF), DNA-binding protein, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | HU, DNA-binding transcriptional regulator, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family. | 0.584 |
| ihfA | rplL | XM1_3138 | XM1_2078 | Integration host factor (IHF), DNA-binding protein, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 50S ribosomal subunit protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.404 |
| ihfA | rplS | XM1_3138 | XM1_0280 | Integration host factor (IHF), DNA-binding protein, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.421 |
| ihfA | rpmF | XM1_3138 | XM1_3135 | Integration host factor (IHF), DNA-binding protein, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 50S ribosomal subunit protein L32; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL32 family. | 0.701 |
| ihfA | rpsO | XM1_3138 | XM1_0334 | Integration host factor (IHF), DNA-binding protein, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 30S ribosomal subunit protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.431 |
| ihfA | rpsT | XM1_3138 | XM1_4792 | Integration host factor (IHF), DNA-binding protein, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.454 |
| rplL | hupB-4 | XM1_2078 | XM1_2743 | 50S ribosomal subunit protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | HU, DNA-binding transcriptional regulator, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family. | 0.404 |
| rplL | ihfA | XM1_2078 | XM1_3138 | 50S ribosomal subunit protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | Integration host factor (IHF), DNA-binding protein, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.404 |