| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XM1_3082 | era | XM1_3082 | XM1_3081 | Protein of unknown function; No homology to any previously reported sequences. | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.768 |
| XM1_3082 | lepB | XM1_3082 | XM1_3079 | Protein of unknown function; No homology to any previously reported sequences. | Signal peptidase I; Function of strongly homologous gene; enzyme; Belongs to the peptidase S26 family. | 0.768 |
| XM1_3082 | recO | XM1_3082 | XM1_3083 | Protein of unknown function; No homology to any previously reported sequences. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.784 |
| XM1_3082 | rnc | XM1_3082 | XM1_3080 | Protein of unknown function; No homology to any previously reported sequences. | RNase III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.768 |
| XM1_3228 | lepB | XM1_3228 | XM1_3079 | Putative Zinc metalloprotease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Signal peptidase I; Function of strongly homologous gene; enzyme; Belongs to the peptidase S26 family. | 0.766 |
| XM1_3228 | yidC | XM1_3228 | XM1_0684 | Putative Zinc metalloprotease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.466 |
| era | XM1_3082 | XM1_3081 | XM1_3082 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Protein of unknown function; No homology to any previously reported sequences. | 0.768 |
| era | lepA | XM1_3081 | XM1_1493 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | GTP-binding membrane protein(Elongation factor, Elongation factor 4,6-597); Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.697 |
| era | lepB | XM1_3081 | XM1_3079 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Signal peptidase I; Function of strongly homologous gene; enzyme; Belongs to the peptidase S26 family. | 0.870 |
| era | recO | XM1_3081 | XM1_3083 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.944 |
| era | rnc | XM1_3081 | XM1_3080 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | RNase III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.937 |
| lepA | era | XM1_1493 | XM1_3081 | GTP-binding membrane protein(Elongation factor, Elongation factor 4,6-597); Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.697 |
| lepA | lepB | XM1_1493 | XM1_3079 | GTP-binding membrane protein(Elongation factor, Elongation factor 4,6-597); Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Signal peptidase I; Function of strongly homologous gene; enzyme; Belongs to the peptidase S26 family. | 0.773 |
| lepA | yidC | XM1_1493 | XM1_0684 | GTP-binding membrane protein(Elongation factor, Elongation factor 4,6-597); Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Putative Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.445 |
| lepB | XM1_3082 | XM1_3079 | XM1_3082 | Signal peptidase I; Function of strongly homologous gene; enzyme; Belongs to the peptidase S26 family. | Protein of unknown function; No homology to any previously reported sequences. | 0.768 |
| lepB | XM1_3228 | XM1_3079 | XM1_3228 | Signal peptidase I; Function of strongly homologous gene; enzyme; Belongs to the peptidase S26 family. | Putative Zinc metalloprotease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.766 |
| lepB | era | XM1_3079 | XM1_3081 | Signal peptidase I; Function of strongly homologous gene; enzyme; Belongs to the peptidase S26 family. | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.870 |
| lepB | lepA | XM1_3079 | XM1_1493 | Signal peptidase I; Function of strongly homologous gene; enzyme; Belongs to the peptidase S26 family. | GTP-binding membrane protein(Elongation factor, Elongation factor 4,6-597); Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.773 |
| lepB | recO | XM1_3079 | XM1_3083 | Signal peptidase I; Function of strongly homologous gene; enzyme; Belongs to the peptidase S26 family. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.865 |
| lepB | rnc | XM1_3079 | XM1_3080 | Signal peptidase I; Function of strongly homologous gene; enzyme; Belongs to the peptidase S26 family. | RNase III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.937 |