| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XM1_3360 | folC | XM1_3360 | XM1_1303 | Dihydroneopterin aldolase; Function of strongly homologous gene; enzyme. | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of strongly homologous gene; putative enzyme; Belongs to the folylpolyglutamate synthase family. | 0.672 |
| XM1_3360 | folE | XM1_3360 | XM1_0397 | Dihydroneopterin aldolase; Function of strongly homologous gene; enzyme. | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.941 |
| XM1_3360 | folK | XM1_3360 | XM1_3358 | Dihydroneopterin aldolase; Function of strongly homologous gene; enzyme. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.996 |
| XM1_3360 | folP | XM1_3360 | XM1_4116 | Dihydroneopterin aldolase; Function of strongly homologous gene; enzyme. | Dihydropteroate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.992 |
| XM1_3360 | ftsH | XM1_3360 | XM1_4117 | Dihydroneopterin aldolase; Function of strongly homologous gene; enzyme. | Protease, ATP-dependent zinc-metallo (Cell division protein FtsH) Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.439 |
| folC | XM1_3360 | XM1_1303 | XM1_3360 | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of strongly homologous gene; putative enzyme; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase; Function of strongly homologous gene; enzyme. | 0.672 |
| folC | folE | XM1_1303 | XM1_0397 | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of strongly homologous gene; putative enzyme; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.672 |
| folC | folK | XM1_1303 | XM1_3358 | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of strongly homologous gene; putative enzyme; Belongs to the folylpolyglutamate synthase family. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.713 |
| folC | folP | XM1_1303 | XM1_4116 | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of strongly homologous gene; putative enzyme; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.992 |
| folC | trpE | XM1_1303 | XM1_3609 | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of strongly homologous gene; putative enzyme; Belongs to the folylpolyglutamate synthase family. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.420 |
| folE | XM1_3360 | XM1_0397 | XM1_3360 | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Dihydroneopterin aldolase; Function of strongly homologous gene; enzyme. | 0.941 |
| folE | folC | XM1_0397 | XM1_1303 | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of strongly homologous gene; putative enzyme; Belongs to the folylpolyglutamate synthase family. | 0.672 |
| folE | folK | XM1_0397 | XM1_3358 | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.997 |
| folE | folP | XM1_0397 | XM1_4116 | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Dihydropteroate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.968 |
| folE | ftsH | XM1_0397 | XM1_4117 | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Protease, ATP-dependent zinc-metallo (Cell division protein FtsH) Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.529 |
| folE | guaB | XM1_0397 | XM1_1579 | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | IMP dehydrogenase(Inosine-5'-monophosphate dehydrogenase,3-478); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.442 |
| folE | trpE | XM1_0397 | XM1_3609 | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.526 |
| folK | XM1_3360 | XM1_3358 | XM1_3360 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Dihydroneopterin aldolase; Function of strongly homologous gene; enzyme. | 0.996 |
| folK | folC | XM1_3358 | XM1_1303 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Bifunctional folylpolyglutamate synthase and dihydrofolate synthase; Function of strongly homologous gene; putative enzyme; Belongs to the folylpolyglutamate synthase family. | 0.713 |
| folK | folE | XM1_3358 | XM1_0397 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | GTP cyclohydrolase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.997 |