| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XM1_2029 | XM1_3029 | XM1_2029 | XM1_3029 | Uroporphyrinogen-III methylase; Function of strongly homologous gene; enzyme. | Putative sulfite reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.913 |
| XM1_2029 | XM1_4238 | XM1_2029 | XM1_4238 | Uroporphyrinogen-III methylase; Function of strongly homologous gene; enzyme. | Putative uroporphyrinogen-III methylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the precorrin methyltransferase family. | 0.903 |
| XM1_2029 | XM1_4239 | XM1_2029 | XM1_4239 | Uroporphyrinogen-III methylase; Function of strongly homologous gene; enzyme. | Conserved protein of unknown function (Cobalamin (vitamin B12) biosynthesis CbiX 12-133; Homologs of previously reported genes of unknown function. | 0.492 |
| XM1_2029 | cobA | XM1_2029 | XM1_0162 | Uroporphyrinogen-III methylase; Function of strongly homologous gene; enzyme. | Uroporphyrinogen-III C-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family. | 0.910 |
| XM1_2029 | cobI | XM1_2029 | XM1_1226 | Uroporphyrinogen-III methylase; Function of strongly homologous gene; enzyme. | Precorrin-2/cobalt-factor-2 C20-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family. | 0.922 |
| XM1_2029 | cysH | XM1_2029 | XM1_3030 | Uroporphyrinogen-III methylase; Function of strongly homologous gene; enzyme. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | 0.756 |
| XM1_2029 | hemB | XM1_2029 | XM1_3372 | Uroporphyrinogen-III methylase; Function of strongly homologous gene; enzyme. | Delta-aminolevulinic acid dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ALAD family. | 0.842 |
| XM1_2029 | hemC | XM1_2029 | XM1_0699 | Uroporphyrinogen-III methylase; Function of strongly homologous gene; enzyme. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.963 |
| XM1_2029 | hemD | XM1_2029 | XM1_0700 | Uroporphyrinogen-III methylase; Function of strongly homologous gene; enzyme. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.921 |
| XM1_2029 | hemE | XM1_2029 | XM1_0834 | Uroporphyrinogen-III methylase; Function of strongly homologous gene; enzyme. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.916 |
| XM1_3029 | XM1_2029 | XM1_3029 | XM1_2029 | Putative sulfite reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Uroporphyrinogen-III methylase; Function of strongly homologous gene; enzyme. | 0.913 |
| XM1_3029 | XM1_4238 | XM1_3029 | XM1_4238 | Putative sulfite reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Putative uroporphyrinogen-III methylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the precorrin methyltransferase family. | 0.911 |
| XM1_3029 | XM1_4239 | XM1_3029 | XM1_4239 | Putative sulfite reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Conserved protein of unknown function (Cobalamin (vitamin B12) biosynthesis CbiX 12-133; Homologs of previously reported genes of unknown function. | 0.448 |
| XM1_3029 | cobA | XM1_3029 | XM1_0162 | Putative sulfite reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Uroporphyrinogen-III C-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family. | 0.905 |
| XM1_3029 | cysH | XM1_3029 | XM1_3030 | Putative sulfite reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | 0.999 |
| XM1_3029 | hemC | XM1_3029 | XM1_0699 | Putative sulfite reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.472 |
| XM1_4238 | XM1_2029 | XM1_4238 | XM1_2029 | Putative uroporphyrinogen-III methylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen-III methylase; Function of strongly homologous gene; enzyme. | 0.903 |
| XM1_4238 | XM1_3029 | XM1_4238 | XM1_3029 | Putative uroporphyrinogen-III methylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the precorrin methyltransferase family. | Putative sulfite reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.911 |
| XM1_4238 | XM1_4239 | XM1_4238 | XM1_4239 | Putative uroporphyrinogen-III methylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the precorrin methyltransferase family. | Conserved protein of unknown function (Cobalamin (vitamin B12) biosynthesis CbiX 12-133; Homologs of previously reported genes of unknown function. | 0.880 |
| XM1_4238 | cobA | XM1_4238 | XM1_0162 | Putative uroporphyrinogen-III methylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen-III C-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family. | 0.909 |