| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XM1_1665 | apt | XM1_1665 | XM1_3706 | Putative Glutamine amidotransferase(Glutamine amidotransferase type 1,44-182); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.943 |
| XM1_1665 | gmk | XM1_1665 | XM1_4495 | Putative Glutamine amidotransferase(Glutamine amidotransferase type 1,44-182); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.923 |
| XM1_1665 | gpt | XM1_1665 | XM1_0601 | Putative Glutamine amidotransferase(Glutamine amidotransferase type 1,44-182); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine. | 0.902 |
| XM1_1665 | guaA | XM1_1665 | XM1_4635 | Putative Glutamine amidotransferase(Glutamine amidotransferase type 1,44-182); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.913 |
| XM1_1665 | surE | XM1_1665 | XM1_3281 | Putative Glutamine amidotransferase(Glutamine amidotransferase type 1,44-182); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Broad specificity 5'(3')-nucleotidase and polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.919 |
| XM1_4496 | gmk | XM1_4496 | XM1_4495 | Homologs of previously reported genes of unknown function. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.934 |
| XM1_4496 | rpoZ | XM1_4496 | XM1_3073 | Homologs of previously reported genes of unknown function. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.544 |
| apt | XM1_1665 | XM1_3706 | XM1_1665 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative Glutamine amidotransferase(Glutamine amidotransferase type 1,44-182); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.943 |
| apt | gmk | XM1_3706 | XM1_4495 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.971 |
| apt | gpt | XM1_3706 | XM1_0601 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine. | 0.932 |
| apt | guaA | XM1_3706 | XM1_4635 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.996 |
| apt | surE | XM1_3706 | XM1_3281 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Broad specificity 5'(3')-nucleotidase and polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.916 |
| gmk | XM1_1665 | XM1_4495 | XM1_1665 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative Glutamine amidotransferase(Glutamine amidotransferase type 1,44-182); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.923 |
| gmk | XM1_4496 | XM1_4495 | XM1_4496 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Homologs of previously reported genes of unknown function. | 0.934 |
| gmk | apt | XM1_4495 | XM1_3706 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.971 |
| gmk | gpt | XM1_4495 | XM1_0601 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine. | 0.920 |
| gmk | guaA | XM1_4495 | XM1_4635 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.974 |
| gmk | ndk | XM1_4495 | XM1_4418 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nucleoside diphosphate kinase ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.931 |
| gmk | pyk | XM1_4495 | XM1_3954 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. | 0.923 |
| gmk | rpoZ | XM1_4495 | XM1_3073 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.941 |