STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
XM1_4591Putative O-acetylhomoserine (thiol)-lyase (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (473 aa)    
Predicted Functional Partners:
metX
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
 
 
 0.974
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.958
metC
Cystathionine beta-lyase, PLP-dependent(Cystathionine beta-lyase, bacterial,5-388); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
0.945
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 
0.940
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.914
oahs
O-acetylhomoserine (thiol)-lyase; Function of strongly homologous gene; enzyme.
  
  
 
0.910
XM1_3708
Putative CoA-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
      0.900
hom
Homoserine dehydrogenase(NAD(P)-binding domain,4-150;Homoserine dehydrogenase, catalytic139-317); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.866
ytkP
Cysteine synthase-like protein; Function of strongly homologous gene; enzyme.
 
 
 0.853
cysK
Cysteine synthase A, O-acetylserine sulfhydrolase A subunit(Cysteine synthase A,18-316); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.850
Your Current Organism:
Magnetospirillum sp. XM1
NCBI taxonomy Id: 1663591
Other names: M. sp. XM-1, Magnetospirillum sp. XM-1
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