STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glxKGlycerate kinase; Belongs to the glycerate kinase type-1 family. (385 aa)    
Predicted Functional Partners:
tadA
tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
 
 
    0.903
gntU
Gnt-I system.
 
  
 0.711
mutX
8-oxo-dGTP diphosphatase.
 
 
    0.655
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.556
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
  
 0.524
CUM71524.1
Putative TrmH family tRNA/rRNA methyltransferase.
       0.515
fruA
EIIABC-Fru.
  
    0.495
murD_2
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
      0.479
CUM84412.1
Putative 2-hydroxyacid dehydrogenase HI_1556; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
   
 0.444
birA
Bifunctional protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
   
    0.424
Your Current Organism:
Roseburia intestinalis
NCBI taxonomy Id: 166486
Other names: DSM 14610, NCIMB 13810, R. intestinalis, Roseburia intestinalis Duncan et al. 2002 emend. Duncan et al. 2006, strain L1-82
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.