STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dacB_2D-alanyl-D-alanine carboxypeptidase dacB precursor; Belongs to the peptidase S11 family. (327 aa)    
Predicted Functional Partners:
dacC
D-alanyl-D-alanine carboxypeptidase dacC precursor; Belongs to the peptidase S11 family.
 
  
 
0.929
dacB_1
D-alanyl-D-alanine carboxypeptidase dacB precursor; Belongs to the peptidase S11 family.
  
  
 
0.924
dacB_3
D-alanyl-D-alanine carboxypeptidase dacB precursor; Belongs to the peptidase S11 family.
  
  
 
0.923
pbpD
Penicillin-binding protein 4 precursor.
 
 
 0.920
mrcA
Penicillin-binding protein 1A.
  
 
 0.908
CUM76294.1
Uncharacterised protein.
  
   0.606
ftsW_1
Cell division protein FtsW; Belongs to the SEDS family.
 
   
 0.599
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
 
 0.572
mgsA_1
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
       0.567
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
  
 
 0.566
Your Current Organism:
Roseburia intestinalis
NCBI taxonomy Id: 166486
Other names: DSM 14610, NCIMB 13810, R. intestinalis, Roseburia intestinalis Duncan et al. 2002 emend. Duncan et al. 2006, strain L1-82
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.