STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysK1O-acetylserine sulfhydrylase. (310 aa)    
Predicted Functional Partners:
mccB
Cystathionine gamma-lyase.
 
 0.983
patB_2
Cystathionine beta-lyase PatB.
  
 0.979
cysE
Serine acetyltransferase.
 
 
 0.976
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
  
 
 0.939
mdeA_3
Methionine gamma-lyase.
 
 
 0.924
cysS
Cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.923
dsvB
Sulfite reductase%2C dissimilatory-type subunit beta; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.907
aspC_2
Aspartate aminotransferase.
   
 0.904
metH
Methionine synthase.
  
 
 0.893
luxS
S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
 
 0.877
Your Current Organism:
Roseburia intestinalis
NCBI taxonomy Id: 166486
Other names: DSM 14610, NCIMB 13810, R. intestinalis, Roseburia intestinalis Duncan et al. 2002 emend. Duncan et al. 2006, strain L1-82
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