STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xerC_4Tyrosine recombinase XerC; Belongs to the 'phage' integrase family. (431 aa)    
Predicted Functional Partners:
uvrA_1
Excinuclease ABC subunit A.
     
 0.611
uvrA_2
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
     
 0.592
CUN27158.1
Acidobacterial duplicated orphan permease.
  
     0.575
CUN30987.1
Transcriptional repressor DicA.
  
    0.560
CUN31388.1
Conjugal transfer relaxase TraA.
  
     0.543
topB_2
DNA topoisomerase 3.
     
 0.515
CUN14696.1
DNA topoisomerase III.
     
 0.515
phoR_7
Alkaline phosphatase synthesis sensor protein phoR.
  
     0.478
dnaK
Heat shock protein 70; Acts as a chaperone; Belongs to the heat shock protein 70 family.
      
 0.450
CUM76018.1
FAD-dependent thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
      
 0.450
Your Current Organism:
Roseburia intestinalis
NCBI taxonomy Id: 166486
Other names: DSM 14610, NCIMB 13810, R. intestinalis, Roseburia intestinalis Duncan et al. 2002 emend. Duncan et al. 2006, strain L1-82
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.