STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
meh3-methylfumaryl-CoA hydratase. (293 aa)    
Predicted Functional Partners:
mct
2-methylfumaryl-CoA isomerase; Belongs to the CoA-transferase III family.
 
 
 0.939
CUX83018.1
beta-methylmalyl-CoA/L-malyl-CoA lyase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.899
mtkA
Malate thiokinase large subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 
  0.893
mtkB
Malate thiokinase small subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
  0.853
mcl2
(3S)-malyl-CoA thioesterase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.698
mcl
beta-methylmalyl-CoA/L-malyl-CoA lyase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.698
CUX83020.1
Serine-glyoxylate aminotransferase apoenzyme.
       0.623
CUX79395.1
formyl-CoA transferase; Belongs to the CoA-transferase III family.
  
 
 0.477
CUX80369.1
Crotonobetainyl-CoA:carnitine CoA-transferase CaiB; Belongs to the CoA-transferase III family.
  
 
 0.477
CUX82618.1
Hypothetical protein.
  
     0.473
Your Current Organism:
Roseibaca calidilacus
NCBI taxonomy Id: 1666912
Other names: R. calidilacus, Rhodobacteraceae bacterium HL-91
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.