STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
truBtRNA pseudouridine55 synthase TruB; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (301 aa)    
Predicted Functional Partners:
infB
Translation initiation factor IF-2 InfB; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
 
 0.966
guaA
GMP synthase (glutamine-hydrolysing) GuaA; Catalyzes the synthesis of GMP from XMP.
  
  
 0.960
rbfA
Ribosome-binding factor RbfA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
  
  
 0.956
rpoC
DNA-directed RNA polymerase beta' subunit RpoC; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.925
rpsO
SSU ribosomal protein S15 RpsO; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
  
 
 0.893
truA
tRNA pseudouridine38-40 synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
 0.878
nusA
Transcription termination protein NusA; Participates in both transcription termination and antitermination.
  
    0.873
rimM
16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
 
  
 0.869
ribF
Bifunctional riboflavin kinase / FMN adenylyltransferase RibF; Belongs to the ribF family.
  
 0.855
trmB
tRNA (guanine-N(7)-)-methyltransferase TrmB; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
 
 
 0.834
Your Current Organism:
Rhodobacteraceae bacterium HLUCCA12
NCBI taxonomy Id: 1666916
Other names: R. bacterium HLUCCA12
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