STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccmBABC-type heme export system permease component CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (206 aa)    
Predicted Functional Partners:
ccmC
ABC-type heme export system permease component CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
 0.999
ccmA
ABC-type heme export system ATPase component CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 0.999
ccmG
Cytochrome c-type biogenesis thiol:disulfide interchange protein CcmG.
 
  
 0.961
ccmE
Cytochrome c-type biogenesis heme chaperone CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
 
 0.947
ccmF
Cytochrome c-type biogenesis protein CcmF.
 
  
 0.881
ccmH
Cytochrome c-type biogenesis protein CcmH; Possible subunit of a heme lyase.
 
   
 0.833
KPQ06452.1
Hypothetical protein.
       0.635
secF
Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
       0.627
secD
Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
       0.625
ccmD
ABC-type heme export system membrane stabilizing component CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
       0.594
Your Current Organism:
Rhodobacteraceae bacterium HLUCCA12
NCBI taxonomy Id: 1666916
Other names: R. bacterium HLUCCA12
Server load: low (10%) [HD]