node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KPQ08073.1 | fabZ | HLUCCA12_03085 | HLUCCA12_03075 | Hypothetical protein. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.868 |
KPQ08073.1 | kdsA | HLUCCA12_03085 | HLUCCA12_12825 | Hypothetical protein. | KDO-8-phosphate synthetase KdsA; Belongs to the KdsA family. | 0.715 |
KPQ08073.1 | kdsB | HLUCCA12_03085 | HLUCCA12_06645 | Hypothetical protein. | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase)e KdsB. | 0.653 |
KPQ08073.1 | kdtA-2 | HLUCCA12_03085 | HLUCCA12_11860 | Hypothetical protein. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.734 |
KPQ08073.1 | lpxA | HLUCCA12_03085 | HLUCCA12_03080 | Hypothetical protein. | UDP-N-acetylglucosamine O-acyltransferase LpxA; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.965 |
KPQ08073.1 | lpxB | HLUCCA12_03085 | HLUCCA12_03090 | Hypothetical protein. | lipid-A-disaccharide synthase LpxB; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.978 |
KPQ08073.1 | lpxC | HLUCCA12_03085 | HLUCCA12_12420 | Hypothetical protein. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase LpxC; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.765 |
KPQ08073.1 | lpxD | HLUCCA12_03085 | HLUCCA12_03900 | Hypothetical protein. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.806 |
KPQ08073.1 | lpxK | HLUCCA12_03085 | HLUCCA12_11060 | Hypothetical protein. | Tetraacyldisaccharide 4'-kinase LpxK; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.812 |
fabZ | KPQ08073.1 | HLUCCA12_03075 | HLUCCA12_03085 | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | Hypothetical protein. | 0.868 |
fabZ | lpxA | HLUCCA12_03075 | HLUCCA12_03080 | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | UDP-N-acetylglucosamine O-acyltransferase LpxA; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.997 |
fabZ | lpxB | HLUCCA12_03075 | HLUCCA12_03090 | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | lipid-A-disaccharide synthase LpxB; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.944 |
fabZ | lpxC | HLUCCA12_03075 | HLUCCA12_12420 | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase LpxC; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.964 |
fabZ | lpxD | HLUCCA12_03075 | HLUCCA12_03900 | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.945 |
fabZ | lpxK | HLUCCA12_03075 | HLUCCA12_11060 | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | Tetraacyldisaccharide 4'-kinase LpxK; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.479 |
ftsZ | lpxC | HLUCCA12_12415 | HLUCCA12_12420 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase LpxC; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.803 |
kdsA | KPQ08073.1 | HLUCCA12_12825 | HLUCCA12_03085 | KDO-8-phosphate synthetase KdsA; Belongs to the KdsA family. | Hypothetical protein. | 0.715 |
kdsA | kdsB | HLUCCA12_12825 | HLUCCA12_06645 | KDO-8-phosphate synthetase KdsA; Belongs to the KdsA family. | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase)e KdsB. | 0.958 |
kdsA | kdtA-2 | HLUCCA12_12825 | HLUCCA12_11860 | KDO-8-phosphate synthetase KdsA; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.803 |
kdsA | lpxA | HLUCCA12_12825 | HLUCCA12_03080 | KDO-8-phosphate synthetase KdsA; Belongs to the KdsA family. | UDP-N-acetylglucosamine O-acyltransferase LpxA; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.846 |