STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdJ2Adenosylcobalamin-dependent ribonucleoside-diphosphate reductase with TSCPD domain NrdJ2; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1232 aa)    
Predicted Functional Partners:
algH
Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.
   
 0.992
grxC
Glutaredoxin 3 GrxC; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
  
 0.937
KPQ15641.1
Glutaredoxin family protein.
  
 0.918
cmk
Cytidylate kinase Cmk.
  
 
 0.901
ndk
Nucleoside-diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.897
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.897
tmk
dTMP kinase Tmk; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.896
gmk
Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP.
     
 0.894
nrdJ1
Adenosylcobalamin-dependent ribonucleoside-diphosphate reductase with TSCPD domain NrdJ1; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
   
 
 
0.867
pyk
Pyruvate kinase Pyk; Belongs to the pyruvate kinase family.
     
 0.865
Your Current Organism:
Rhodobacteraceae bacterium HLUCCO18
NCBI taxonomy Id: 1666917
Other names: R. bacterium HLUCCO18
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