STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPM_0012Threonine synthase and cysteate synthase. (317 aa)    
Predicted Functional Partners:
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
 
 0.984
CPM_0210
Threonine dehydratase.
 
 
 0.964
CPM_0011
NAD dependent epimerase/dehydratase family.
 
     0.954
CPM_1395
Threonine synthase and cysteate synthase.
  
  
 
0.927
CPM_0590
Homoserine dehydrogenase.
 
 
 0.861
CPM_0010
PP-loop superfamily ATPase fused to Zn-finger domain.
       0.860
CPM_0382
Aspartate kinase.
 
 
 0.793
CPM_1676
3-isopropylmalate dehydratase small subunit.
  
  
 0.712
thiI
tRNA S(4)U 4-thiouridine synthase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
    0.699
pdxS
Pyridoxal phosphate synthase subunit PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
  
    0.617
Your Current Organism:
Cuniculiplasma divulgatum
NCBI taxonomy Id: 1673428
Other names: C. divulgatum, Cuniculiplasma divulgatum Golyshina et al. 2016, JCM 30642, Thermoplasmatales archaeon PM4, Thermoplasmatales archaeon S5, VKM B-2941, strain S5
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