STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPM_0214Isocitrate dehydrogenase. (403 aa)    
Predicted Functional Partners:
CPM_0277
Aconitate hydratase.
  
 0.995
CPM_0403
Malate dehydrogenase; Belongs to the LDH/MDH superfamily.
 
 
 0.963
CPM_1207
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.958
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
  
 0.955
CPM_0252
2-oxoacid ferredoxin oxidoreductase subunit gamma-alpha.
  
 
 0.920
CPM_1378
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.920
CPM_0253
2-oxoacid ferredoxin oxidoreductase subunit beta.
    
 0.916
CPM_1377
2-oxoglutarate ferredoxin oxidoreductase subunit beta.
    
 0.916
CPM_0785
Molybdopterin binding domain protein.
      0.898
CPM_0879
Adenylosuccinate lyase.
    
 0.866
Your Current Organism:
Cuniculiplasma divulgatum
NCBI taxonomy Id: 1673428
Other names: C. divulgatum, Cuniculiplasma divulgatum Golyshina et al. 2016, JCM 30642, Thermoplasmatales archaeon PM4, Thermoplasmatales archaeon S5, VKM B-2941, strain S5
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