STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPM_0218Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (225 aa)    
Predicted Functional Partners:
lipA
Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 0.998
CPM_1335
Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
  
  
 
0.917
CPM_0220
2-oxoacid dehydrogenase multienzyme complex, dihydrolipoyl acyltransferase (E2) component.
 
 
 0.877
CPM_0222
2-oxoacid dehydrogenase multienzyme complex, 2-oxoacid decarboxylase (E1) component subunit alpha.
     
 0.827
CPM_0219
2-oxoacid dehydrogenase multienzyme complex, dihydrolipoamide dehydrogenase (E3) component.
  
  
 0.822
CPM_0221
2-oxoacid dehydrogenase multienzyme complex, 2-oxoacid decarboxylase (E1) component subunit beta.
     
 0.810
gcvH
Glycine cleavage system H protein (lipoate-binding); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
 0.745
rpl37e
50S ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family.
   
 0.401
Your Current Organism:
Cuniculiplasma divulgatum
NCBI taxonomy Id: 1673428
Other names: C. divulgatum, Cuniculiplasma divulgatum Golyshina et al. 2016, JCM 30642, Thermoplasmatales archaeon PM4, Thermoplasmatales archaeon S5, VKM B-2941, strain S5
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