STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mptAGTP cyclohydrolase IV; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (297 aa)    
Predicted Functional Partners:
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.
     
 0.904
CPM_1477
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
  
  0.849
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
    
  0.802
CPM_0431
NUDIX family hydrolase.
     
  0.800
pfdB
Prefoldin subunit beta; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
       0.800
CPM_1078
N6-threonylcarbamoyl-adenosine(37)-tRNA synthase dimerization module Pcc1.
       0.772
CPM_0405
6-pyruvoyl-tetrahydropterin synthase.
 
   
 0.600
CPM_0199
Rossmann fold enzyme.
 
   
 0.570
CPM_0759
Dihydroorotase.
  
  
 0.544
mptD
Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
 
   
 0.522
Your Current Organism:
Cuniculiplasma divulgatum
NCBI taxonomy Id: 1673428
Other names: C. divulgatum, Cuniculiplasma divulgatum Golyshina et al. 2016, JCM 30642, Thermoplasmatales archaeon PM4, Thermoplasmatales archaeon S5, VKM B-2941, strain S5
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