STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPM_1945Glycine/serine hydroxymethyltransferase. (429 aa)    
Predicted Functional Partners:
CPM_1943
Glycine cleavage system T protein (aminomethyltransferase).
 
 0.998
CPM_0005
Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.
  
 0.978
CPM_0411
Glycine dehydrogenase subunit 2.
 
 
 0.972
folD
Bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
 0.972
CPM_1738
Phosphoribosylglycinamide formyltransferase.
  
 0.969
gcvH
Glycine cleavage system H protein (lipoate-binding); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
  
 
 0.962
CPM_0410
Glycine dehydrogenase subunit 1.
 
 
 0.962
fhs
Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family.
  
 0.958
CPM_0814
Phosphoserine phosphatase.
  
 0.935
CPM_0087
Dihydrolipoamide dehydrogenase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 0.934
Your Current Organism:
Cuniculiplasma divulgatum
NCBI taxonomy Id: 1673428
Other names: C. divulgatum, Cuniculiplasma divulgatum Golyshina et al. 2016, JCM 30642, Thermoplasmatales archaeon PM4, Thermoplasmatales archaeon S5, VKM B-2941, strain S5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.